Artificial Transcription Factors Increase Production of Recombinant...
AbstractA randomized library that encodes for artificial zinc finger protein transcription factors (ZFP-TF) was constructed and screened for components that increased production of a monoclonal...
View ArticleExpression and purification of recombinant human Angiopoietin-1 produced in...
AbstractAngiopoietin-1 (Ang1) is an essential molecule for blood vessel formation. In an effort to produce large quantities of Ang1, recombinant Chinese hamster ovary (rCHO) cells expressing a high...
View ArticleHigh-level Expression and Purification of a Designed Angiopoietin-1 Chimeric...
AbstractA designed angiopoietin-1 (Ang1) chimeric protein with nonleaky angiogenic activity, COMP-Ang1, is an effective alternative to native Ang1 for therapeutic angiogenesis in vivo. Recombinant...
View ArticleEffects of culture temperature and pH on flag-tagged COMP angiopoietin-1...
AbstractTo maximize the production of flag-tagged cartilage oligomeric matrix protein angiopoietin-1 (FCA1) from Chinese hamster ovary (CHO) cells, the effects of culture pH and temperature on cell...
View ArticleMolecular epidemiology of norovirus in asymptomatic food handlers in Busan,...
AbstractThe molecular epidemiology of norovirus infections was studied in food handlers without any symptoms from January to December 2015 in Busan city, Korea. A total of 2,174 fecal specimens from...
View ArticleEvaluation of Physicochemical and Biological Stability of 36-Months-Aged SB5...
AbstractIntroductionTumor necrosis factor (TNF-alpha) inhibitors, such as adalimumab, have shown success in treating autoimmune inflammatory diseases but are associated with substantial financial...
View ArticleExtended Stability of Reconstituted and Diluted SB3 (Trastuzumab Biosimilar)...
AbstractIntroductionStability information for the trastuzumab biosimilar SB3 is limited to 48 h at 2–8 °C for the reconstituted solution and 24 h at up to 30 °C for diluted solutions. Extended...
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